best choice is to see whether you can time-shift your day. i commuted past the 95S ramp on Rt 2 for several years, and that segment of 95 from 2 to 90 is nearly always scrod during rush hour (S in the morning, N in the evening is worst, but don't count on the opposite direction being any better).

if you don't want to sit in traffic for hours every week, check to see whether the framingham/worcester commuter rail out of south station goes anywhere near the office you're working in.